View the NORC Membership Application (pdf)

Membership guidelines

Membership in the Washington University Nutrition Obesity Research Center (NORC) Core Center is available to Washington University faculty who have a professional interest in obesity, clinical nutrition, nutrition education or nutrition-related research.

Regular Membership Requirements

  • Full-time Washington University faculty
  • PI of nutrition/obesity-related research grant
  • Plan to use a NORC Core laboratory for nutrition/obesity-related research

Associate Membership Requirements

  • Full-time Washington University faculty involved in nutrition/obesity-related research or clinical activities, but does not meet all criteria for Regular membership
  • May include Co-I of nutrition/obesity-related research grant in which the PI is a NORC Regular Member, current NORC P&F Program recipient, and/or no active extramural nutrition nutrition/obesity research funding, but is a NORC Core Director or Associate Director still conducting nutrition/obesity research with departmental or other funds.

Membership privileges

Members will be able to attend conferences, seminars and retreats sponsored by the NORC Core Center at no cost. Members will have priority use of shared resources and services offered by the NORC including:

  • Animal Model Research Core: Provides expert consultation and training in the use of animal models and technical procedures, and specific services including biochemical analyses of lipids and glucose in small volume serum and tissue samples, body composition analyses, and assessment of energy metabolism and balance.  New services have been added to include in vivo substrate metabolism analyses in rodents.
  • Cellular and Molecular Biology Core: Provides high resolution respirometry in intact tissues, cells and isolated mitochondria, analysis of circulating biomarkers relevant to obesity (adipokines, hepatokines, myokines and cytokines), adipose tissue immune cell isolation, murine brown/beige adipose tissue isolation and characterization, starter cultures for adipogenic murine embryonic fibroblasts, and expansion of extracellular vesicle (EV) analysis.
  • Clinical Science Research Core: Provides consultation in study design and selection of outcome measures, body composition analysis, protocol-specific meals for diet intervention studies, stable isotopically labeled metabolic tracer and hormone infusate preparation, clinical services to obtain muscle and adipose tissue biopsies and conduct cardiovascular testing, inpatient and outpatient sleep monitoring services, and assistance in implementing lifestyle interventions.  Offers metabolic kinetic assessments using stable isotope tracers ad mathematical modeling of both tracer and non-tracer data.
  • Dissemination and Implementation Science Core: Provides NORC investigators with the support needed to incorporate dissemination and implementation science into their nutrition and obesity research programs at any translational stage, thereby ultimately accelerating knowledge from scientific discovery to equitable healthcare delivery.

Current Members

Regular NORC Members

Abumrad, Nada A IM – G&NS Molecular mechanisms of fatty acid trafficking
Apte, Rajendra Ophthalmology & Visual Science NAD biology and macrophage cholesterol metabolism and age-related macular degeneration
Artyomov, Maxim N Pathology & Immunology Metabolic regulation of immune cell activation
Baldridge, Megan T IM – Infectious Diseases Effect of intestinal commensal microbes and pathogens on host health
Bateman, Randall J Neurology CNS protein metabolism in obesity & Alzheimer’s Disease
Baumann-Dudenhoeffer, Aimee M. Pediatrics Neonatal gut microbiome development
Bennett, Kevin M Radiology Noninvasive MRI evaluation of chronic kidney disease (CKD)
Bernal-Mizrachi, Carlos IM – Endocrinology & Metabolism Vitamin D metabolism and cardiovascular disease
Binder, Ellen F IM – G&NS Nutrition and exercise on physical frailty in older adults
Brestoff, Jonathan R Pathology & Immunology Role of cell-to-cell transfer of mitochondria in regulating metabolism
Brookheart, Rita T IM – G&NS The role of Site-1 Protease (S1P) in regulating skeletal muscle metabolism and function
Brownson, Ross C School of Social Work & Public Health Community interventions to reduce obesity and prevent chronic disease
Carter, Ebony B OBGYN Interventions that improve maternal and infant outcomes in pregnant women with obesity or diabetes
Cavazos-Rehg, Patricia Psychiatry Technology-based (social media) investigations of eating disorders and depression
Colonna, Marco Pathology & Immunology Immune function in obesity
Dantas, Gautam Pathology & Immunology Tunable therapeutic modulation of the gut microbiome by engineered probiotics
Davidson, Nicholas O IM – Gastoenterology Intestinal and hepatic lipoprotein metabolism
DeBosch, Brian J Pediatrics – Gastroenterology Nonalcoholic fatty liver disease (NAFLD) and cardiomyopathy
Diwan, Abhinav IM – Cardiovascular Division Lysosome biology and the role of autophagy in obesity and cardiovascular disease
Evanoff, Bradley IM – General Medical Sciences Worksite intervention to promote healthy eating and weight control
Eyler, Amy A School of Social Work & Public Health Implementation of state and local nutrition and physical activity policies to prevent and manage diabetes
Finck, Brian N IM – G&NS Hepatic and cardiac lipid metabolism
Fitzsimmons-Craft, Ellen E Psychiatry Technology-based eating and weight disorder prevention, screening and treatment
Gordon, Jeffrey I Laboratory & Genomic Medicine Role of gut microbiota in metabolic function and obesity
Gropler, Robert J Radiology Myocardial metabolism and mechanical function in health and disease
Gross, Richard W IM – Bioorganic Chemistry & Molecular Pharmacology Molecular mechanisms of insulin resistance and diabetes
Guilak, Farshid Orthopaedic Surgery Obesity, biomechanics, and inflammation in osteoarthritis
Haire-Joshu, Debra School of Social Work & Public Health Community-based interventions for obesity and diabetes
Hastings, Mary K Physical Therapy Adverse effects of obesity and type 2 diabetes (T2D) on muscle, bone, skin and joint structures in the lower leg
Henderson, Jeffrey P IM – Infectious Diseases Metabolic mechanisms of nutritional immunity in the urinary tract
Herrick, Cynthia J IM – Endocrinology & Metabolism Obesity and diabetes prevention and management in low socioeconomic patients
Hershey, Tamara G Psychiatry Dopamine function and obesity-related eating behavior
Holtzman, David M Neurology Apolipoprotein E and lipids in Alzheimer’s disease
Hughes, Jing W IM – Endocrinology & Metabolism Glucagon regulation by a novel brown adipose factor
Iannotti, Lora School of Social Work & Public Health Developing solutions to prevent and treat undernutrition in low-resource settings
Imai, Shin-ichiro Developmental Biology NAD metabolism and aging
Ippolito, Joseph Radiology Sex differences in cancer metabolism
Javaheri, Ali IM – Cardiovascular Division Role of lipid metabolism and autophagy in determining cardiac structure, function and remodeling after injury
Ju, Yo-El S Neurology Bi-directional relationships among sleep, metabolic function and neurodegenerative diseases
Kast, David JE Cell Biology & Physiology Regulation of lipid droplet biogenesis and catabolism
Klein, Samuel IM – G&NS Understanding the mechanisms responsible for metabolic abnormalities associated with obesity and the therapeutic metabolic effects of weight loss
Kravitz, Alexxai V Psychiatry Investigating the mechanisms responsible for regulating hedonic eating behavior in obesity
Lavine, Kory J IM – Cardiology Macrophage functions and influence cardiac tissue repair mechanisms
Liu, Yongjian Radiology Targeted molecular probes for atherosclerosis imaging and therapy
Lodhi, Irfan J IM – Endocrinology & Metabolism Adipocyte biology and metabolism
Lowe, Mark E. Pediatrics Role of lipases in dietary fat digestion; Role of genetic variants in the pathogenesis of chronic pancreatitis and complications including pancreatic exocrine insufficiency
Lucey, Brendan P Neurology The association between amyloid-β kinetics, age, amyloid levels, and the amyloid-β day/night pattern
Meyer, Gretchen A Physical Therapy Muscle-fat signaling in muscle degeneration and regeneration
Milbrandt, Jeffrey D Pathology & Immunology Nutrition and axonal degeneration/regeneration
Millman, Jeffrey R IM – Endocrinology & Metabolism Human stem cell differentiation to insulin-producing β cells for diabetes cell replacement therapy
Mittendorfer, Bettina IM – G&NS Diet and metabolic function and muscle protein metabolism in aging
Musiek, Erik S Neurology Cellular and molecular mechanisms of neurodegeneration
Nichols, Colin G Cell Biology & Physiology Electrical control of insulin secretion
Nicol, Ginger E Psychiatry Prevention and treatment of obesity in people with mental health disorders
Norris, Aaron Anesthesiology CNS regulation of energy balance with emphasis on sleep, stress, and opioid system signaling
Pagliarini, David J Cell Biology & Physiology Composition, function and regulation of the mitochondrial proteome and its relationship to human disease
Park, Yikyung Surgery Modifiable lifestyle factors in relation to health outcomes
Patnode, Michael L Pathology & Immunology Interaction between dietary fiber intake, the gut microbiome and metabolic health
Patti, Gary J Chemistry A comprehensive platform for high-throughput metabolome profiling
Peterson, Linda R IM – Cardiology Obesity and cardiovascular risk
Peterson, Lindsay L IM – Medical Oncology The link between advanced glycation end products and breast cancer
Peterson, Timothy R IM – Bone & Mineral Diseases Novel insulin-sensitizing NASH/diabetes drugs
Pincus, Zachary S Genetics Mechanisms determining inter-individual differences in lifespan, and differences in individual health during aging using model organism C. elegans
Province, Michael A Genetics Complex trait human gene discovery and validation
Racette, Susan B Physical Therapy Diet and exercise interventions for obesity and disease prevention
Rajagopal, Rithwick Ophthalmology & Visual Science Pathogenic mechanisms in diabetic retinopathy and neuronal damage in diabetes
Randolph, Gwendalyn J Pathology & Immunology Lymphatic system in obesity and cardiometabolic disease
Razani, Babak IM – Cardiology Role of macrophage lysosomal biogenesis in atherosclerosis and cardiac dysfunction of obesity
Sah, Rajan IM – Cardiovascular Division Ion channel SWELL1, an important regulator of adipocyte function and metabolism
Samovski, Dmitri IM – G&NS Endosomal pathway in metabolic targeting of fatty acids
Schechtman, Kenneth B IM – Biostatistics Effectiveness of family-based weight loss treatment implemented in primary care
Schilling, Joel D IM – Cardiology Macrophage metabolism and inflammation in metabolic disease
Semenkovich, Clay F IM -Endocrinology & Metabolism Molecular mechanisms responsible for the pathophysiology of obesity, diabetes and atherosclerosis
Shaw, Paul J Neuroscience Functional analysis of sleep promoting neurons in health and disease
Shen, Hua Orthopaedic Surgery The roles of adipose-derived stem cell extracellular vesicles in regulating tendon inflammation and metabolism
Silva, Matthew J Orthopedic Surgery Mechanobiology of bone
Stitziel, Nathan O IM – Cardiology Contribution of genetic variations in lipoprotein metabolism to cardiometabolic disease
Tabak, Rachel G Prevention Research Center Dissemination and implementation of lifestyle interventions to reduce obesity and diabetes
Teitelbaum, Steven L Pathology & Immunology Effect of nutrition and inflammation on bone metabolism
Thompson, Michael D Pediatrics -Endocrinology & Diabetes Impact of maternal obesity on offspring liver disease and metabolic health
Urano, Fumihiko IM – Endocrinology & Metabolism Endoplasmic reticulum stress and metabolic function
Van Tine, Brian IM – Medical Oncology Metabolism in sarcomas
Veis, Deborah IM – Bone & Mineral Diseases Role of mitochondrial dynamics in bone homeostasis
Vlassenko, Andrei G Radiology Aerobic glycolysis in the development of Alzheimer’s Disease
von Morze, Cornelius J Radiology Novel hyperpolarized 13C molecular imaging techniques for differentiating NAFLD and NASH
Warner, Brad W Surgery Mechanisms involved in intestinal adaption after massive resection
Wilfley, Denise E Psychiatry Causes, prevention and treatment of obesity and eating disorders
Woodard, Pamela K Radiology Use of PET tracers to assess cardiovascular structure and function in people
Zayed, Mohamed A Surgery Influences of diabetes on peripheral arterial disease

Associate NORC Members

Name Primary Department Research Focus
Alpers, David H IM – Gastroenterology Synthesis, secretion and transcytotic movement of intestinal proteins
Cabassa, Leopoldo J Social Work Physical and mental health disparities among racial/ethnic minorities with severe mental illness
Colditz, Graham A Surgery Associations between obesity and cancer causes, prevention and survival
Davila-Roman, Victor G IM – Cardiovascular Cardiovascular imaging, hypertension and heart failure
de las Fuentes, Lisa IM – Cardiovascular Genetic variants in myocardial metabolism and inflammation
Eagon, Christopher J Surgery Surgical treatment of obesity
Eisenstein, Sarah A Psychiatry Dopamine signaling and reward-related behavior using PET neuroimaging in obesity and schizophrenia
Farabi, Sarah S IM – G&NS Biobehavioral mechanisms related to obesity
Frolova, Antonina OBGYN Effects of maternal obesity and dyslipidemia on myometrial contractility, labor and obstetric outcomes
Goyal, Manu S Radiology Imaging, genomic and metabolomic investigations in the human brain
Jacome-Sosa, Miriam M IM – G&NS Novel therapeutic approaches for the management of obesity, type 2 diabetes and gastrointestinal diseases
Lawson, Heather Genetics How diet modifies genetic and epigenetic effects in metabolically normal and abnormal obese people
Ley, Timothy J IM – Bone Marrow Transplant Using mouse models of acute myeloid leukemia (AML) to establish key principles of AML pathogenesis
Okunade, Adewole L IM – G&NS Establishing new methods for in vivo and in vitro metabolic research
Palanisamy, Arvind Anesthesiology Childhood obesity after labor induction with Oxytocin
Parra Perez, D Prevention Research Center Chronic disease prevention as related to physical activity, nutrition and obesity
Patterson, Bruce W IM – G&NS Stable isotope tracer methodology in the study of protein, fat and carbohydrate metabolism in humans
Powers Carson, Jennifer L IM – Endocrinology & Metabolism Biomarkers for diabetes progression and complication
Raghuraman, Nandini OBGYN Intrauterine resuscitation and intrapartum maternal and fetal physiology
Reeds, Dominic N IM – G&NS Metabolic abnormalities in patients with HIV infection and interventions that improve insulin sensitivity
Reeds, Susan R IM – Weight Management Obesity as a chronic illness
Schwarz, Julie K Radiation Oncology Association of genomic mutations in PIK3CA and PTEN with cervical cancer treatment response and glucose uptake
Shoghi, Kooresh I Radiology Biology of disease mechanisms, engineering and imaging sciences and informatics
Smith, Gordon I IM – G&NS Use of stable isotope methods to study human protein and fat metabolism in vivo
Stein, Richard I IM – G&NS Lifestyle change treatments for obesity and eating disorders
Su, Xiong IM – G&NS Molecular mechanisms mediating insulin signaling and lipid metabolism in metabolic diseases
Tosti, Valeria IM – G&NS Metabolic effects of protein restriction, calorie restriction, intermittent fasting and the Mediterranean diet in humans
Yoshino, Mihoko IM – G&NS Metabolic effects of weight loss in type 2 diabetes

IM=Internal Medicine; G&NS=Geriatrics and Nutritional Science

Please acknowledge the Washington University NORC, Nutrition Obesity Research Center,  in your publications by: “Supported by NIH grant P30 DK056341 (Nutrition Obesity Research Center).”