Longevity Research Program

John O. Holloszy, MD (left) and Luigi Fontana, MD, PhD, are leading research efforts aimed at determining whether calorie restriction can slow the progress of aging and lengthen life in humans.

John O. Holloszy, MD (left) and Luigi Fontana, MD, PhD, are leading research efforts aimed at determining whether calorie restriction can slow the progress of aging and lengthen life in humans.

A joint enterprise of Washington University School of Medicine and the Reinsurance Group of America, the Longer Life Foundation has as its mission:

To study factors that assist in predicting mortality and morbidity of selected populations and to research methods to promote improvements in longevity and health by analyzing the effects of changes in medicine and advances in public health practices.

For more than 15 years, the Longer Life Foundation has awarded grant funding to investigators with novel ideas for advancing their research. Calls for applications have ranged from novel cancer screenings, mental health issues, frailty, brain injuries and obesity, among many others. The Longer Life Foundation seeks to fund research studying determinants of long term prognosis for common ailments in the public. Preference is given to clinical research. Studies that research methods to improve disease prognosis or prevent ailments from occurring, thereby improving quality and quantity of life, are of particular interest. We are interested in pilot and feasibility studies as well as research as a component of larger or established studies, such as analyses of existing databases.

View current LLF call for applications »

Adminstration

Dominic Reeds, MD, with the administrative support of Rachel Hauck, provides overall supervision of the Longer Life Center (LLC). Dr. Reeds also directs the Longer Life Foundation (LLF) Enrichment and Dissemination Program and works with Dan Zimmerman, MD, on education programs, position papers and opportunities for hosting international fellows. David Alpers, MD, directs the Research Program, including chairing the Scientific Review Committee (SRC), presenting the SRC’s reports to the LLF Advisory Group and mentoring grantees who are young investigators.

The Scientific Review Committee, which reviews grant applications, consists of a multidisciplinary group of Washington University faculty and members of the Reinsurance Group of America; it is focused on critical appraisal of applications to the foundation.

Joan Heins, along with her duties as Assistant Secretary of the Foundation, serves as both Administrator of the LLC and Director of the Tracking and Evaluation Program. LLC personnel provide a novel, contemporary interface between the Foundation and Washington University. This facilitates functions such as identifying speakers for insurance meetings, securing clinical specialists to provide updates and continuing education to varied insurance groups, and promoting activities of the Foundation within the Washington University community. This group also works closely with Pat Gregory in the Washington University Office of Corporate and Foundation Affairs to develop strategies for attracting additional funding to the Foundation.

Administrative core

Administrator: R. Hauck


Longer Life Center

Director: D. Reeds


Research program

Director: D. Alpers


Tracking and evaluation

Director: J. Heins


Scientific review committee

Chair: D. Alpers
Members: D. Haire-Joshu, S. Klein, R. Brownson, C. Holowaty, P. Miller, T. Cade, D. Rengachary, B. Margolis, D. Zimmerman, P. Quartararo


Enrichment and dissemination program

Director: D. Reeds


Longer Life Center 

 


Board of Governors Advisory Group

Managing Director: D. Zimmerman


Longer Life Foundation

 


Office of Corporate and Foundation Affairs

P. Gregory
E. Ruzicka